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Sunday, May 22, 2016

Brufen 400 mg Tablets Uses, Side Effects & Interactions

Ibuprofen (Brufen) 400mg


Ibuprofen Information

Ibuprofen is a kind of drug that belongs to the group of medicines called non-steroidal anti-inflammatory drugs or NSAIDs. Ibuprofen functions in the body by blocking the action of a substance in the body called cyclo-oxygenase that is involve in the production of various chemicals in the body such as prostaglandins that causes inflammation, pain, and swelling. In other words, Ibuprofen is used to relieve pain and inflammation.
NSAIDs medicines such as Ibuprofen reduce inflammation caused by the body’s own immune system. Ibuprofen is an effective painkiller. Ibuprofen relieves pain such as muscular aches and pains, headache, backache, period pains, rheumatic pains, neuralgia, and dental pains. Ibuprofen also reduces the symptoms of colds and flu.

 Ibuprofen (Brufen) 400mg

Ibuprofen Interactions

Drinking alcohol when taking ibuprofen may increase the risk of stomach bleeding.
According to the US Food and Drug Administration, "ibuprofen can interfere with the antiplatelet effect of low-dose aspirin, potentially rendering aspirin less effective when used for cardioprotection and stroke prevention." Allowing sufficient time between doses of ibuprofen and immediate-release (IR) aspirin can avoid this problem. The recommended elapsed time between a dose of ibuprofen and a dose of aspirin depends on which is taken first. It would be 30 minutes or more for ibuprofen taken after IR aspirin, and 8 hours or more for ibuprofen taken before IR aspirin. However, this timing cannot be recommended for enteric-coated aspirin. But, if ibuprofen is taken only occasionally without the recommended timing, the reduction of the cardioprotection and stroke prevention of a daily aspirin regimen is minimal.

Ibuprofen Warnings

Ibuprofen belongs to the FDA pregnancy category B for first two trimesters and FDA pregnancy category D for third trimesters. Consult your doctor first before taking Ibuprofen if you are pregnant or planning to be pregnant. Ibuprofen may cause severe defects to an unborn baby. It is always safe to use Ibuprofen during pregnancy if you discuss with your doctor the benefits and the risks that Ibuprofen may cause to the mother and to the unborn baby.
Studies show that Ibuprofen passes into the breast milk, but in such small quantities, it is unlikely to harm an infant. Still, consider to consult you doctor first before you breast-feed a baby to run off from gaining unwanted side effects.
Exercise caution while using Ibuprofen in children. Some preparations of Ibuprofen may not be suitable for children under certain ages. Caution is also needed in the elderly and in people with impaired kidney, liver, or heart function. Kidney function of anybody that will take Ibuprofen medicine must always be monitored.
Before you use Ibuprofen, tell your doctor first whether you have the following conditions:

  • Hypertension or High Blood Pressure
  • Bleeding Disorders
  • Decreased heart function
  • Decrease Liver function
  • Decrease Kidney function
  • Asthma or History of asthma
  • History of Allergies
  • History of Diseases of the stomach or intestines
Ibuprofen is not to be used in patients with the following conditions:

  • Peptic ulcer or History of Peptic ulcer
  • Allergy to Aspirin or to any other ingredients of Ibuprofen
  • History of Bronchospasm or narrowing of airways
  • History of Rhinitis or inflammation of the nasal membranes

Ibuprofen Uses

Ibuprofen is used primarily to treat fever (including postimmunisation fever), mild to moderate pain (including pain relief after surgery), painful menstruation, osteoarthritis, dental pain, headaches, and pain from kidney stones. About 60% of people respond to any NSAID; those who do not respond well to a particular one may respond to another.
It is used for inflammatory diseases such as juvenile idiopathic arthritis and rheumatoid arthritis. It is also used for pericarditis and patent ductus arteriosus.

Ibuprofen Intake Guidelines

Follow exactly from your doctor’s direction on using Ibuprofen. You may also ask your doctor, pharmacist, or nurse for other things which you do not understand.
Take each dose of Ibuprofen with a full glass of water. Ibuprofen should be taken with food, milk, or an antacid for reason to lessen stomach upsets.
For additional information on how to take Ibuprofen, you may ask your doctor. It is important to consult your doctor first before you make any medical-concern decisions.

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Ibuprofen Dosage

Obtain your Ibuprofen dose from your doctor. Dosage of Ibuprofen drug may vary from person to person. The following data are just the usual dosage of Ibuprofen drug.
For the treatment of Rheumatoid arthritis and Osteoarthritis, the dosage of Ibuprofen is 300 mg, 400mg, 600mg, or 800mg. This dosage of Ibuprofen should be adjusted according to client response. Full response may not be noted still until two or more week is past.
For the treatment of Juvenile arthritis, the dosage of Ibuprofen is 30-70mg/kg per day in three to four divided doses and 20mg/kg per day may be adequate for mild cases.
For the treatment of Mild to moderate pain in adult, the dosage of Ibuprofen is 400 mg every 4-6 hours as needed.
For the treatment of Antipyretic in pediatric with 2-12 years of age, the dosage of Ibuprofen is 5mg/kg if baseline temperature is 102.5°F (39.1°C) and below 10mg/kg if baseline temperature is greater than 102.5°F (39.1°C). The maximum daily dose of Ibuprofen is 40mg/kg.
For the treatment of Primary dysmenorrheal in adult, the dosage of Ibuprofen is 400mg every 4 hour as needed.
For the treatment of Mild to moderate pain, antipyretic, and dysmenorrheal, the dosage of Ibuprofen is 200mg every 4-6 hours. This dosage of Ibuprofen may be increased to 400mg if pain or fever continues. Dosage of Ibuprofen should not exceed 1,200 mg per day.
For the treatment of Pain and fever in children with 2-11 years of age, the dosage of Ibuprofen is 7.5mg/kg up to a maximum dose of 30mg/kg per day.

Ibuprofen OverDose

Symptoms of overdose of Ibuprofen may include the following:

  • Nausea
  • Vomiting
  • Stomach pain
  • Dizziness
  • Drowsiness
  • Headache
  • Blurred vision
  • Numbness
  • Little or no urine production
  • Slow breathing
  • Ringing in the ears
  • Seizures
  • Sweating
Immediately seek for a medical attention if you experience any of the above stated conditions.
Ibuprofen Missed Dose
You can get the most suitable result if you do not miss any dose of Ibuprofen. If it is unavoidable for you to miss a dose of Ibuprofen, take the missed dose immediately as soon as you remember up to 2 hours late. If more than 2 hours have passed since the missed dose, skip the missed and the next regular scheduled dose. It is important not to take a double dose of Ibuprofen medication.

Ibuprofen Side Effects

Side effects of Ibuprofen may include the following:

  • Liver disorders
  • Kidney Damage
  • Dyspepsia or Indigestion
  • Blood disorders
  • Disturbances of the gut such as diarrhea, nausea, vomiting, or abdominal pain
  • Fluid Retention
  • Epidermal Necrolysis
  • Bleeding from the stomach or intestine
  • Stomach or Duodenal Ulcer
  • Headache
  • Meningitis
  • Rash
  • Dizziness
  • Allergic reactions such as skin rashes, swelling of the lips, tongue, and throat
Other side effects caused by Ibuprofen may also occur. Consult your doctor immediately if you experienced the above given side effects or if you feel anything unusual or bothersome effects.

Ibuprofen Drug Reactions

The following other medicines may interfere with the work of Ibuprofen or may even worsen the situation:
 Blood thinning or Anti-clothing medicines such as Warfarin. The use of these said products may increase the risk of bleeding from the gut.
Corticosteroids such as Prednisone. The use of these medicines may increase the risk of side effects such as stomach irritation.
Amlodipine and other Antihypertensive medicines. Ibuprofen decreases the effects of these medicines.
Diuretics, ACE inhibitors or Ciclosporin. Using these products together with Ibuprofen may increase the risk of kidney problems.
Other NSAIDs medicines. Taking nay other NSAIDs medicines with Ibuprofen may increase the risk of side effects.

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In some countries IBUPROFEN may also be known as: Advil, Apsifen, Arthrofen, Brufen, Cuprofen, Ebufac, Fenbid, Galprofen, Genpril, Haltran, Ibrufhalal, Ibu, Ibufac, Ibufem, Ibugel, Ibular, Ibuleve, Ibumousse, Ibuspray, Inoven, Isisfen, Junifen, Librofem, Lidifen, Manorfen, Menadol, Migrafen, Motrin, Novaprin, Orbifen, PhorPain, Relcofen, SeclodinU, niprofen, ACT-3, Actiprofen, Rafen, Tri-Profen, Novo-Profen, Cipgesic, Emflam, Ibugesic, Ibupal, Ibucare, Panafen, Profinal, Artril, Bebol, Ibu-600, Biophen, Anadin Ultra, Biatain-Ibu, Feverfen, Hedex Ibuprofen, Ibuleve, Pedea, Phor Pain, Radian-B Ibuprofen, Ibu-Tab, Ibu-4, -6, -8, Ibu, Cramp & Body Aches, NeoProfen, Saleto-200, Femicaps, Femmex Plus, Pedibu, Lumbax 

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